Hidden 19S IgM rheumatoid factor in adults with juvenile rheumatoid arthritis onset.
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چکیده
منابع مشابه
Hidden 19S IgM rheumatoid factor in adults with juvenile rheumatoid arthritis onset.
Forty-eight adult patients with juvenile rheumatoid arthritis (JRA) (onset before age 16 years) were evaluated at the age of 17 years or more for the presence of hidden 19S IgM rheumatoid factors (RF), i.e., 19S IgM RF that can be detected by the complement-dependent haemolytic assay in the IgM-containing fraction after separation of the serum by acid gel filtration. The average age of the pati...
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IgM rheumatoid factors capable of complement fixation and activation are commonly present in the sera of adults with rheumatoid arthritis. Hidden complement fixing IgM rheumatoid factor has been demonstrated in the majority of patients with juvenile RA and hidden agglutinating IgM rheumatoid factors have been demonstrated in the serum of adults with seronegative rheumatoid arthritis. We studied...
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OBJECTIVES To determine the presence of immunoglobulin E-rheumatoid factor in patients with juvenile rheumatoid arthritis and to correlate it with clinical and laboratory parameters. METHODS A multicenter prospective study was carried out from January 1993 to January 1999 with the enrollment of 3 centers of pediatric rheumatology. Ninety-one children with juvenile rheumatoid arthritis diagnos...
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The serological diagnosis of juvenile rheumatoid arthritis (JRA) is difficult, with only 7-10% of patients 19S IgM rheumatoid factor positive. About 60-70% of patients are positive for hidden 19S IgM rheumatoid factor, but this test requires serum separation and is not available in most laboratories. Antiperinuclear factor has been described in both seropositive and seronegative adult patients ...
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Usual techniques for the detection of antigammaglobulin factors (DAT, SCAT, HEAT, Latex FII) are based upon agglutination reactions and are therefore useful when IgM antibodies are involved. It is well known that antiglobulins also belong to IgG and IgA classes. In our experience, 50 per cent. of patients with JRA are persistently seronegative when sera are tested only with conventional aggluti...
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ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 1985
ISSN: 0003-4967
DOI: 10.1136/ard.44.5.294